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2022/04/15

JCM strains requiring co-culture

 The resident microbiota such as human oral and intestinal microbiota is more than we could imagine. It is composed of a wide variety of bacterial species, many of which are uncultured and unclassified bacterial species. Among the strains deposited in recent years, there are unique strains that require co-cultivation with other strain (helper strain). Fretibacterium fastidiosum (JCM 16858T), isolated from the oral cavity, is a bacterial species belonging to the Synergistetes phylum. This strain requires Fusobacterium nucleatum subsp. nucleatum as a helper strain. Tannerella serpentiformis (JCM 31301, JCM 31302 and JCM 31303T) is associated with human oral health. These strains require Cutibacterium acnes (formerly Propionibacterium acnes subsp. acnes) as a helper strain. Two strains of Unidentified bacterium JCM 31632 and JCM 31633 have also been deposited as the first cultivated strain of phylotype Anaerolineae bacterium HOT-439 belonging to the oral cavity-derived Chloroflexi phylum. These strains require Fusobacterium nucleatum subsp. polymorphum as a helper strain. It is expected that the symbiotic mechanism of microbiota will be unraveled by further isolating and culturing strains requiring co-culture in the future. We would be happy if our resources could be useful for your research.

Fretibacterium fastidiosum JCM 16858T
(with helper strain: vertical line)
Tannerella serpentiformis JCM 31303T
(with helper strain : vertical lines)
Tannerella serpentiformis JCM 31303T
(Cells of JCM 31303T)
Unidentified bacterium JCM 31632
(with helper strain: vertical line)


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